Table 3.
Top enrichment results associated with macular thickness
| Term | Description | Observed/total genes | P | FDR | |
|---|---|---|---|---|---|
| Disease | |||||
| PA444119 | Eye diseases | 70/437 | 1.1E-11 | 2.3E-08 | |
| PA443521 | Blindness | 36/96 | 3.4E-08 | 3.8E-05 | |
| PA443320 | Amblyopia | 15/45 | 1.3E-07 | 9.5E-05 | |
| PA444117 | Eye abnormalities | 32/189 | 1.3E-06 | 6.4E-04 | |
| PA445532 | Retinal diseases | 42/285 | 1.4E-06 | 6.4E-04 | |
| PA445530 | Retinal degeneration | 36/234 | 2.9E-06 | 1.1E-03 | |
| PA165108137 | Retinitis NOS | 31/194 | 6.4E-06 | 2.0E-03 | |
| PA443989 | Ectopia lentis | 7/13 | 7.5E-06 | 2.1E-03 | |
| PA445537 | Retinitis pigmentosa | 31/197 | 8.8E-06 | 2.2E-03 | |
| PA447310 | Vision disorders | 21/112 | 1.7E-05 | 3.8E-03 | |
| KEGG | |||||
| hsa05210 | Colorectal cancer––Homo sapiens (human) | 18/62 | 8.0E-07 | 2.4E-04 | |
| hsa05213 | Endometrial cancer––Homo sapiens (human) | 15/52 | 7.3E-06 | 8.5E-04 | |
| hsa05161 | Hepatitis B––Homo sapiens (human) | 28/146 | 8.5E-06 | 8.5E-04 | |
| hsa05200 | Pathways in cancer––Homo sapiens (human) | 56/397 | 1.2E-05 | 8.8E-04 | |
| hsa05203 | Viral carcinogenesis––Homo sapiens (human) | 34/205 | 2.6E-05 | 1.5E-03 | |
| hsa01521 | EGFR tyrosine kinase inhibitor resistance––Homo sapiens (human) | 18/81 | 4.7E-05 | 2.0E-03 | |
| hsa05230 | Central carbon metabolism in cancer––Homo sapiens (human) | 16/67 | 4.9E-05 | 2.0E-03 | |
| hsa05215 | Prostate cancer––Homo sapiens (human) | 19/89 | 5.3E-05 | 2.0E-03 | |
| hsa04915 | Estrogen signaling pathway––Homo sapiens (human) | 20/100 | 9.0E-05 | 3.0E-03 | |
| hsa05222 | Small cell lung cancer––Homo sapiens (human) | 18/86 | 1.1E-04 | 3.0E-03 |