Table 1.

Summary of protein quantification data. Three strains with double resistance to nitazoxanide (NTZ) and to metronidazole (MET), namely C4, 10621D10, and 713M3 and their respective wild-type strains WBC6, 106 and 713 were grown (the resistant strains in the presence of 50 μM MET or NTZ), harvested and subjected to MS shotgun analysis as described in Materials and methods. For each strain, three biological replicates have been tested (with three technical replicates per biological replicate).

	WBC6 vs. C4	106 vs. 10621D10	713 vs. 713M3
Unique peptides	21048	16567	16587
Non-redundant proteins	1607	1403	1452
Differential NTZ	225	248	304
Differential MET	510	287	216