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. 2019 Feb 5;19(4):2569–2580. doi: 10.3892/mmr.2019.9937

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Copyright: © Huang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Overview of lncRNAs differentially expressed between 8 patients with DCM and 8 controls, detected by RNA sequencing. (A) Hierarchical clustering of partial differentially expressed lncRNAs. (B) Heat map of partially dysregulated lncRNAs. (C) A total of 88,768 lncRNAs were detected by RNA sequencing. Among these, 988 lncRNAs were differentially expressed between patients with DCM and controls, including 661 upregulated and 327 downregulated lncRNAs. (D) A scatter plot of the total lncRNAs between patients with DCM and controls. The criteria used included a fold-change of ≥2 or ≤-2, and a P-value of <0.05. Ctrl, control; DCM, dilated cardiomyopathy; lncRNA, long noncoding RNA.