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. 2019 Feb 5;19(4):2569–2580. doi: 10.3892/mmr.2019.9937

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Copyright: © Huang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Overview of mRNAs differentially expressed between patients with DCM (n=8) and controls (n=8), determined by RNA sequencing. (A) Brief RNA sequencing results of mRNAs. A total of 20,315 mRNAs were detected from the mRNA expression profile analysis. Among these, 1,418 mRNAs were differentially expressed between patients with DCM and controls, including 800 upregulated and 618 downregulated mRNAs. (B) Scatter plot of mRNAs. The criteria included a fold-change of ≥2 or ≤-2, and a P-value of <0.05. (C) Top 10 upregulated and top 10 downregulated mRNAs with the highest fold-change. mRNA, messenger RNA; DCM, dilated cardiomyopathy.