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PTEN is direct target of miR-17-5p. (A) Sequence alignment of the paired 3′-UTR of miR-17-5p and PTEN by bioinformatics tool Targetscan and miRanda; (B) Results of dual luciferase reporter assay. **P<0.01. WT, Fragments of wild-type PTEN 3′-UTR; Mutant, fragments of wild-type PTEN 3′-UTR; NC, miR-17-5p negative control; PTEN, Phosphatase and tensin homolog; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.
