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Correlations between regional CBF and vessel histology. Notable associations were observed between CBF values and vessel area in the (A) F-P cortex and (B) thalamus in APP/PS1 mice aged 2 and 3.5 mo, but not 5 and 8 mo. CBF units, ml/100 g·min; Vessel area unit: µm2/mm2. *P<0.05 and **P<0.01. CBF, cerebral blood flow; F-P, frontoparietal; mo, months old.
