Figure 4.
Knockdown of PADI4 inhibits the migration and invasion ability of A549 cell. (A) The migration potential of A549 cells and shPADI4 A549 cells determined by wound-healing assay (magnification, ×200) and the statistical results are presented. (B) The invasion potential of A549 cells and shPADI4 A549 cells assessed by Transwell assay (magnification, ×400) and the statistical chart. Differences among groups were analyzed by one-way analysis of variance, followed by Bonferroni's multiple comparison test. *P<0.05 vs. Ctrl, n=3. sh, short hairpin; PADI4, protein-arginine deiminase type-4; Ctrl, control; NC, negative control.