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Rab7 promotes the Ras/Raf/MEK/ERK signaling pathway. Expression of proteins associated with the Ras/Raf/MEK/ERK signaling pathway in Rab7 knockdown (A; Case 4) and overexpression (B; Case 8) in human aortic smooth muscle cells were analyzed by western blotting. MAPK, mitogen-activated protein kinase; MEK, MAPK kinase; p, phosphorylated; siRab7, small interfering RNA Rab7.
