Skip to main content
. 2019 Apr;47(4):425–435. doi: 10.1124/dmd.118.084269

Fig. 2.

Fig. 2.

(A) Relative CYP2C9 Vivid enzyme activity. Bar graphs show normalized Vivid enzymatic activity of the CYP2C9 WT and variant proteins (nanomolar fluorescent product formed per minute per milligram of total protein); error bars depict S.D. of the mean in three independent activity assays. (B) Relative CYP2C19 Vivid enzyme activity. Bar graphs show normalized Vivid enzymatic activity of the CYP2C19 WT and variant proteins (nanomolar fluorescent product formed per minute per milligram of total protein); error bars depict S.D. of the mean in three experimental samples. Enzyme activity was analyzed using one-way ANOVA, with mean comparison for each variant genotype against the WT control performed using Dunnet’s test. Corresponding P values were multiplicity adjusted and reported as such. *P ≤ 0.05; **P ≤ 0.01; ***P ≤ 0.001.