Table 5.
Group contrast | Connectivity between
ROIs |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
ROI | Region | x | y | z | ROI | Region | x | y | z | t | F | |
Control > PTS | ||||||||||||
10 | L. middle temporal gyrus | −68 | −23 | −16 | 17 | R. middle cingulate | 8 | −48 | 31 | 4.256 | 8.940 | |
16 | L. posterior cingulate | −3 | −49 | 13 | 29 | L. dorsolateral PFC | −20 | 45 | 39 | 4.462 | 11.533 | |
8 | L. superior temporal gyrus | −44 | 12 | −34 | 38 | L. anterior cingulate | −3 | 42 | 16 | 4.143 | 9.611 | |
5 | L. ventromedial PFC | −18 | 63 | −9 | 57 | L. ventrolateral PFC | −46 | 31 | −13 | 4.046 | 9.836 | |
PTS > Control | ||||||||||||
2 | R. orbitomedial PFC | 6 | 67 | −4 | 18 | R. precuneus | 15 | −63 | 26 | 4.601 | 10.656 | |
18 | R. precuneus | 15 | −63 | 26 | 37 | L. dorsomedial PFC | −2 | 38 | 36 | 4.231 | 11.552 | |
18 | R. precuneus | 15 | −63 | 26 | 40 | L. dorsomedial PFC | −8 | 48 | 23 | 4.257 | 7.987 | |
23 | L. dorsomedial PFC | −10 | 39 | 52 | 58 | R. ventrolateral PFC | 49 | 35 | −12 | 3.935 | 9.806 | |
42 | L. middle temporal gyrus | −56 | −13 | −10 | 58 | R. ventrolateral PFC | 49 | 35 | −12 | 4.310 | 10.926 | |
Control > mTBI + PTS | ||||||||||||
8 | L. superior temporal gyrus | −44 | 12 | −34 | 17 | R. middle cingulate | 8 | −48 | 31 | 4.888 | 13.266 | |
23 | L. dorsomedial PFC | −10 | 39 | 52 | 32 | L. anterior cingulate | −7 | 51 | −1 | 5.645 | 15.953 | |
mTBI + PTS > Control | ||||||||||||
— | — | |||||||||||
PTS > mTBI + PTS | x | y | z | x | y | z | ||||||
10 | L. middle temporal gyrus | −68 | −23 | −16 | 14 | R. precuneus | 6 | −59 | 35 | 5.085 | 14.383 | |
2 | R. orbitomedial PFC | 6 | 67 | −4 | 18 | R. occipital/precuneus | 15 | −63 | 26 | 3.848 | 10.656 | |
3 | R. ventromedial PFC | 8 | 48 | −15 | 18 | R. occipital/precuneus | 15 | −63 | 26 | 3.977 | 7.980 | |
2 | R. orbitomedial PFC | 6 | 67 | −4 | 19 | L. middle cingulate | −2 | −37 | 44 | 3.842 | 6.299 | |
4 | L. precuneus | −13 | −40 | 1 | 26 | R. dorsolateral PFC | 22 | 39 | 39 | 3.722 | 10.956 | |
23 | L. dorsomedial PFC | −10 | 39 | 52 | 32 | L. anterior cingulate | −7 | 51 | −1 | 4.528 | 15.953 | |
23 | L. dorsomedial PFC | −10 | 39 | 52 | 35 | R. orbitomedial PFC | 8 | 42 | −5 | 4.163 | 11.720 | |
18 | R. occipital/precuneus | 15 | −63 | 26 | 37 | L. dorsomedial PFC | −2 | 38 | 36 | 3.751 | 11.552 | |
23 | L. dorsomedial PFC | −10 | 39 | 52 | 37 | L. dorsomedial PFC | −2 | 38 | 36 | 3.716 | 8.390 | |
25 | L. dorsolateral PFC | −35 | 20 | 51 | 39 | L. frontopolar | −20 | 64 | 19 | 3.938 | 8.222 | |
25 | L. dorsolateral PFC | −35 | 20 | 51 | 41 | R. middle temporal gyrus | 65 | −12 | −19 | 3.747 | 8.963 | |
42 | L. middle temporal gyrus | −56 | −13 | −10 | 48 | R. middle temporal gyrus | 52 | −2 | −16 | 3.709 | 6.014 | |
18 | R. occipital/precuneus | 15 | −63 | 26 | 52 | R. cerebellum | 28 | −77 | −32 | 4.113 | 7.995 | |
24 | L. dorsolateral PFC | −16 | 29 | 53 | 57 | L. ventrolateral PFC | −46 | 31 | −13 | 4.124 | 6.094 | |
25 | L. dorsolateral PFC | −35 | 20 | 51 | 57 | L. ventrolateral PFC | −46 | 31 | −13 | 4.059 | 6.729 | |
35 | R. orbitomedial PFC | 8 | 42 | −5 | 57 | L. ventrolateral PFC | −46 | 31 | −13 | 4.510 | 8.304 | |
23 | L. dorsomedial PFC | −10 | 39 | 52 | 58 | R. ventrolateral PFC | 49 | 35 | −12 | 4.012 | 9.806 | |
30 | R. dorsomedial PFC | 6 | 54 | 16 | 58 | R. ventrolateral PFC | 49 | 35 | −12 | 3.639 | 8.671 | |
mTBI + PTS > PTS | ||||||||||||
6 | L. middle temporal gyrus | −46 | −61 | 21 | 28 | L. dorsolateral PFC | −10 | 55 | 39 | 3.913 | 7.667 | |
9 | R. middle temporal pole | 46 | 16 | −30 | 28 | L. dorsolateral PFC | −10 | 55 | 39 | 3.596 | 6.028 | |
14 | R. precuneus | 6 | −59 | 35 | 42 | L. middle temporal gyrus | −56 | −13 | −10 | 4.129 | 10.637 |
Abbreviations: mTBI, mild traumatic brain injury; PFC, prefrontal cortex; PTS, posttraumatic stress symptoms; ROIs: regions of interest.