| Molecular classification | Grade I recommendations | Grade III recommendations |
|---|---|---|
| After a pathological diagnosis of gastric cancer, molecular profiling should be conducted and treatment should be guided according to the molecular classification | All cases of gastric adenocarcinoma should undergo HER2 assessmenta–d (Evidence 1A) | |
| Molecular profiling related to prognosis of gastric cancer | HER2 assessmente,f (Evidence 3) MSI/MMR detectiong,h (Evidence 3) |
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