Table 3.
Hazard ratios and 95% confidence intervals of all-cause mortality, myocardial infarction and stroke by weight-change categories; sensitivity analysis excluding subjects with the occurrence of end points within 1 year of follow-up
| Weight change (%) | Myocardial infarction | Stroke | All-cause mortality | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Events (n) | Incidence rate (per 1000 person-years) | HR (95% CI) | Events (n) | Incidence rate (per 1000 person-years) | HR (95% CI) | Events (n) | Incidence rate (per 1000 person-years) | HR (95% CI) | |
| ≥ − 10% | 57 | 2.43 | 1.20 (0.91,1.58) | 65 | 2.77 | 1.01 (0.78,1.30) | 180 | 7.64 | 1.74 (1.48, 2.03) |
| − 10 ~ − 5% | 197 | 2.27 | 1.13 (0.96,1.33) | 197 | 2.27 | 0.90 (0.77,1.06) | 433 | 4.97 | 1.22 (1.09, 1.36) |
| − 5 ~ 5% | 870 | 2.09 | 1 (ref.) | 1056 | 2.54 | 1 (ref.) | 1614 | 3.87 | 1 (ref.) |
| 5 ~ 10% | 126 | 2.15 | 1.01 (0.83,1.22) | 163 | 2.78 | 1.10 (0.94,1.30) | 306 | 5.19 | 1.28 (1.14, 1.45) |
| ≥ 10% | 55 | 2.52 | 1.18 (0.89,1.55) | 77 | 3.54 | 1.35 (1.06,1.70) | 140 | 6.39 | 1.58 (1.33, 1.88) |
Adjusted for age, sex, alcohol drinking, smoking, regular exercise, income status, baseline fasting glucose levels, dyslipidemia, hypertension, waist circumferences, insulin use and estimated glomerular filtration rate. HR hazard ratios, CI confidence intervals