Table 1.

The neuroprotective effects of TCM herbs involves anti- inflammatory responses in IRI rodent models.

TCM herb	Rodent type	Anti-inflammatory target	Cerebral IRI-model	Reference
Ilex pubescens	Mice/rat	NO↓, IL-1β↓, TNF-α↓, TNOS↓, iNOS↓, cNOS↓ IL-10↑, NOS↓	BCCAO/MCAO	Fang et al., 2017; Yan et al., 2017
Carthamus tinctorius L.	Rat	IL-1β↓, TNF-α↓	BCCAO	Fu et al., 2016
Gastrodia	Rat	NO↓, iNOS↓, nNOS↓	MCAO	Zeng et al., 2006; He et al., 2016; Xian et al., 2016
Dracocephalum moldavica L.	Rat	TNF-α↓, IL-6↓, IL-8↓	MCAO	Jia J.X. et al., 2017
Sophora japonica	Rat	IL-1β↓	MCAO	Lao et al., 2005
Ganoderma lucidum	Rat	TNF-α↓, IL-8↓	MCAO	Zhang W. et al., 2014
Panax notoginseng	Mice	Trx-1↓, NF-κB↓, HSP70↓	MCAO	Zeng et al., 2014
Acanthopanax polysaccharides	Rat	IL-10↑, IL-1β↓, TNF-α↓	MCAO	Xie et al., 2015
Rabdosia rubescens	Rat	NO↓, NOS↓, IL-1β↓, TNF-α↓	MCAO	Miao et al., 2017
Rhizoma Pinelliae Pedatisectae	Rat	IL-1β↓, TNF-α↓	MCAO	Ye et al., 2016
Kudiezi	Patient	IL-6↓, IL-18↓, IL-10↑	IS	Liu X. et al., 2018