Table 3.

The neuroprotective effects of TCM formula and decoction involves anti- inflammatory responses in IRI rodent models.

TCM	Rodent type	Anti-inflammatory target	Cerebral IRI- Model	Reference
Gueichih-Fuling-Wan	Rat	iNOS↓, COX-2↓, NO↓	BCCAO	Chen et al., 2016
Herbal formula FBD	Mice	PMNs↓, TNF-α↓, IL-1↓ IL-8↓, N F-κB↓	BCCAO	Lin et al., 2008
Naoxintong	Mice	LOX-1↓, pERK1/2↓, NF-κB↓	MCAO	Xue et al., 2016
Shaoyao-Gancao	Rat	IL-1β↓, TNF-α↓, MCP-1↓, IL-10↓, NeuN↑, IBA1↓, GFAP↓	MCAO	Zhang et al., 2016
Danshen-Chuanxiong-Honghua	Mice	IL-6↓, IL-1β↓, TNF-α↓	MCAO	Zhang et al., 2017
Tao-Hong-Si-Wu-Tang	Rat	HIF-1α↓, TNF-α↓, iNOS↓	MCAO	Wu et al., 2011
Xueshuantong	Rat	IL-1β↓, IL-17↓, IL-23p19↓, TNF-α↓, iNOS↓, Prx6↓, TLR4↓, p38↓, STAT3↑	MCAO	Wang X. et al., 2015
Huangjiao granules	Rat	IL-10↑, PI3K↑, p-AKT↑, p-mTOR↑, IL-1β↓, TNF-α↓	MCAO	Pan et al., 2017
ZiYin HuoXue JieDu	Rat	IL-1β↓, TNF-α↓, IL-8↓	MCAO	Chunyan et al., 2011
Shengmai san	Rat	TNF-α↓, NO↓	BCCAO	Li et al., 2013
Yokukansan	Gerbils	Iba1↓	BCCAO	Zhou et al., 2014
Weinaokang	Mice	MMP-9↓, p-ERK1/2↓, GRK2↓, NO↓, NOS↓	BCCAO	Zheng et al., 2010