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. 2019 Mar 8;10:231. doi: 10.3389/fphys.2019.00231

FIGURE 4.

FIGURE 4

Effects of fecal microbiota transplantation (FMT) on brain PVN pro-inflammatory markers expression. mRNA levels of TNF-α (A), IL-β (B), IL-6 (C), IL-17a (D), interferon-γ (IFNγ) (E), IL-10 (F), C-C chemokine ligand 2 (CCL2) (G) and macrophage marker CD11b (H) measured by RT-PCR in brain PVN from all experimental groups. Strain factor, FMT factor and I interaction between strain and FMT factors. ++p < 0.01, +p < 0.05 and ns (not significant) for the probability based on a two-way analysis of variance. Values are means ± SEM (n = 5–8). ∗P < 0.05 and ∗∗P < 0.01 vs. WKY with stool transplant from WKY (W-W); #P < 0.05 vs. SHR with stool transplant from SHR (S-S), statistical significance for the probability based on a Sidak’s correction multiple comparisons test.