Table 1.
1,8-Cineole maintained the balance of cytokines secretion in the serum of LPS-induced mice.
| Group (mg/kg) | IL-6 (pg/ml) | IL-8 (pg/ml) | IL-10 (pg/ml) |
|---|---|---|---|
| Vehicle | 50.82 ± 11.68 | 64.64 ± 5.99 | 75.14 ± 2.36 |
| LPS (1) | 223.88 ± 15.16## | 481.19 ± 11.50## | 11.73 ± 2.15## |
| Dexamethasone (5) | 34.71 ± 3.61** | 183.90 ± 17.50** | 20.94 ± 1.92** |
| 1,8-Cineole (50) | 157.07 ± 6.01** | 270.81 ± 19.47** | 23.32 ± 1.92** |
| 1,8-Cineole (100) | 50.82 ± 11.68** | 183.41 ± 7.70** | 25.70 ± 4.77** |
| 1,8-Cineole (200) | 9.85 ± 0.24** | 90.96 ± 4.90** | 57.76 ± 5.71** |
Protein levels of IL-6, IL-8, and IL-10 in serum of LPS-induced mice were determined by an ELISA kit according to manufacturer’s instructions. Data are the mean ± SD (n = 6). ##P < 0.01 vs. vehicle; ∗∗P < 0.01 vs. LPS group.