Table 3.
Haemodynamic changes during the study period
| Baseline | Post Induction | Post Intubation | Pre prone | 5 min Post prone | 10 min Post Prone | 15 min Post Prone | 20 min Post Prone | P | |
|---|---|---|---|---|---|---|---|---|---|
| CO (L/min) | 3.77±1.09 | 3.47±0.84 | 3.9±1.01 | 3.74±0.95 | 3.62±0.96 | 3.61±1 | 3.54±1.03 | 3.49±1.04 | 0.186 |
| CI (L/min/m2) | 2.25±0.59 | 2.06±0.46 | 2.32±0.54 | 2.23±0.51 | 2.17±0.56 | 2.17±0.59 | 2.12±0.63 | 2.1±0.64 | 0.224 |
| HR (beats/min) | 81±14 | 81±13 | 93±12† | 85±13 | 85±15 | 76±13‡ | 75±11‡ | 74±11‡ | <0.001 |
| SV (mL) | 46.4±10.8 | 43.9±12.6* | 42.6±11.1 | 44.0±12.1 | 42.9±11.8 | 48.7±13.8 | 48.3±14.1† | 48.8±16.6† | 0.002 |
| SVI (mL/m2) | 27.8±5.8 | 26.2±6.9* | 25.7±6.1 | 26.3±6.8 | 25.9±6.9 | 29.3±8.3† | 29.1±8.4† | 29.3±10.1† | 0.005 |
| SVV (%) | 16.8±3.6 | 16.4±2.9 | 16.7±2.74 | 16.3±2.8 | 16.4±2.3 | 15.9±3.0 | 15.6±3.1* | 15.1±3.4* | 0.008 |
| MAP (mm Hg) | 113.23±12.26 | 96.03±17.51† | 125.8±23.55* | 98.7±19.52* | 91.93±19.93† | 86.83±21.6† | 83.7±15.15†,‡ | 78.63±13.87†,‡ | <.001 |
| TPR (dynes/sec/cm5) | 2637.27±709.24 | 2337.47±700.03 | 2805.7±770.5 | 2297.83±660.55 | 2152.47±643.8 | 2006.1±710.64† | 2003.07±599.28† | 1923.9±579.83† | <.001 |
| TPRI (dynes/sec/cm5/m2) | 4374.5±1049.67 | 3863.73±1053.77 | 4633.53±1151.42 | 3812.57±1045.41 | 3574.2±1050.63 | 3283.77±1132.86† | 3333.5±1007.76† | 3221±1068.71† | <.001 |
CO – Cardiac output, CI – Cardiac index, HR – Heart rate, SV – Stroke volume, SVI – Stroke volume index, SVV – Stroke volume variation, MAP – Mean arterial pressure, TPR – Total peripheral vascular resistance, TPRI – Total peripheral vascular resistance index. All values are in mean±SD. *P<0.05 compared to baseline, †P<0.01 compared to baseline, ‡P<0.05 compared to pre-prone