Table 4 –
Factors associated with subsequent antibiotic exposure after intracerebral hemorrhage
| Characteristic | Unadjusted odds ratio (95%CI) |
P value |
|---|---|---|
| Age, per decade | 0.83 (0.74 – 0.93) | 0.001 |
| Male sex | 2.17 (1.49 – 2.97) | <0.001 |
| Temperature | ||
| >38.3 °C | 1.92 (1.40 – 2.65) | <0.001 |
| >38.9 °C | 1.49 (1.03 – 2.17) | 0.04 |
| WBC > 12k/dL | 1.19 (0.81 – 1.54) | 0.49 |
| Bandemia >10% | 1.90 (0.90 – 4.01) | 0.09 |
| Number of SIRS criteria met | 1.38 (1.16 – 1.64) | <0.001 |
| Infiltrates on chest imaging | 3.62 (2.06 – 6.39) | <0.001 |
| Microbiology results | ||
| Blood – true positive | Unable* | -- |
| Blood – false positive | 4.09 (1.08 – 15.55) | 0.04 |
| Sputum – true positive | 2.97 (1.88 – 4.67) | <0.001 |
| Sputum – false positive | 3.27 (2.17– 4.94) | <0.001 |
| Urine – true positive | 3.65 (1.76 – 7.54) | <0.001 |
| Urine – false positive | 1.54 (0.82 – 2.88) | 0.18 |
Only one subject in this category, precluding regression.
Abbreviations: WBC – White blood cell count; SIRS – Systemic inflammatory response syndrome.