Table 1.
Baseline characteristics of acute Chagas' disease patients treated with benznidazol
| Group | ||||
|---|---|---|---|---|
| Variable | Total (n = 63) | Cardiac alterations (n = 21) | No Cardiac alterations (n = 42) | p-value |
| Age (y) | 29 [16-44] | 38 [15-44] | 26.5 [17-44] | 0.694* |
| Gender | 0.588† | |||
| Male | 38 (60%) | 14 (67%) | 24 (57%) | |
| Female | 25 (40%) | 7 (33%) | 18 (43%) | |
| Transmission | 0.364† | |||
| Oral | 47 (75%) | 14 (67%) | 33 (79%) | |
| Vector | 16 (25%) | 7 (33%) | 9 (21%) | |
| Case | 0.044† | |||
| Outbreak | 44 (70%) | 11 (52%) | 33 (79%) | |
| Isolated | 19 (30%) | 10 (48%) | 9 (21%) | |
| Origin (Mesoregion) | 0.020† | |||
| Central Amazonas | 13 (21%) | 9 (43%) | 4 (10%) | |
| North Amazonas | 15 (24%) | 3 (14%) | 12 (29%) | |
| Southwest Amazonas | 33 (53%) | 9 (43%) | 24 (59%) | |
| South Amazonas | 1 (2%) | - | 1 (2%) | |
| T. cruzi DTU | 0.355† | |||
| TcI | 2 (3%) | 2 (9%) | - | |
| TcIV | 11 (17%) | 2 (9%) | 9 (21%) | |
| Z3 (TcIII/TcIV) | 22 (35%) | 9 (43%) | 13 (31%) | |
| ND | 28 (44%) | 8 (38%) | 20 (48%) | |
| Follow-up period (y) | 15.5 ± 4.1 | 14 ± 4 | 16.4 ± 4.1 | 0.050** |
Data are expressed as median [IQ25%-IQ75%] and mean ± SD; In parenthesis are the percentage of the total group; ND: not described; Obs.: It was not possible to obtain the provenance of one case.
*
Wilcoxon rank-sum (Mann-Whitney) test.
**
Unpaired t-test (Student t test).
†
Fisher's exact test.