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. 2019 Feb 20;16:141–154. doi: 10.1016/j.omtn.2019.02.009

Figure 8.

Figure 8

Summarizing Illustration on the Role of Alternative Chromatin Structures on Gene-Editing Outcomes

The thickness of the curved arrows represents the relative contribution of homology-directed repair (HDR) and non-homologous end joining (NHEJ) pathways to gene-editing endpoints at euchromatin versus KRAB-controlled heterochromatin.