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Ablation of NK3R neurons in the MnPO did not alter circadian rhythms of (A, B) TSKIN or (C, D) activity in (Left) OVX or (Right) OVX + E2 mice. The data were binned into 3-hour blocks (beginning at 7:00 am) for statistical comparisons. Black bars on the x-axes denote the dark phase. n = 7 to 9 mice per group. +P < 0.01, OVX vs OVX + E2, within blank-SAP; #P < 0.05, OVX vs OVX + E2, within NK3-SAP.
