Liu 2010.
Methods |
Allocation: parallel, randomised Blind: not stated Setting: hospital (inpatient), single centre Country: China Length of study: 4 weeks |
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Participants |
Diagnosis: schizophrenia (CCMD‐3) Total N at randomisation = 72 Sex: male 35, female 37 Age (years): mean 38.42, SD 6.15 Length of illness (years): not stated History: not stated Exclusion criteria: patients with severe physical illness; alcohol or drug abusers. |
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Interventions |
ECT group (n = 35): MECT + antipsychotics Content: participants received antipsychotic therapy such as chlorpromazine, clozapine, perphenazine, and risperidone, and also received MECT. The ECT device was Thymatron. Frequency: 3 times a week for MECT; not stated for antipsychotics Course of treatment (MECT): 12 sessions Treatment duration: 28 days Control group (n = 37): Antipsychotics alone Content: participants received antipsychotic therapy such as chlorpromazine, clozapine, perphenazine, and risperidone. Frequency: not stated Treatment duration: 28 days |
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Outcomes | Mental state: assessed by SAPS, SANS Unable to use: Response to treatment (data not reported) |
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Notes | Contact information: Shaoyang Psychiatric Hospital, Shaoyang, Hunan, China | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "...were divided randomly into two groups..." (p.29) Comments: The author described a random component in the sequence generation process, but no details were provided on randomisation method. |
Allocation concealment (selection bias) | Unclear risk | Comments: The author did not describe the allocation concealment. Insufficient information to permit judgement of 'low risk' or 'high risk'. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Comments: The participants and personnel could not be blinded as 1 group did not use ECT, and no sham‐ECT was used. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comments: The author did not describe the blinding of outcome assessment. Insufficient information to permit judgement of 'low risk' or 'high risk'. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Comments: No missing outcome data. |
Selective reporting (reporting bias) | High risk | Comments: The protocol is not available; all outcomes stated in methods other than overall efficiency rate reported in results. |
Other bias | Low risk | None obvious. |