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. 2019 Mar 19;2019(3):CD011847. doi: 10.1002/14651858.CD011847.pub2

Liu 2010.

Methods Allocation: parallel, randomised
Blind: not stated
Setting: hospital (inpatient), single centre
Country: China
Length of study: 4 weeks
Participants Diagnosis: schizophrenia (CCMD‐3)
Total N at randomisation = 72
Sex: male 35, female 37
Age (years): mean 38.42, SD 6.15
Length of illness (years): not stated
History: not stated
Exclusion criteria: patients with severe physical illness; alcohol or drug abusers.
Interventions ECT group (n = 35): MECT + antipsychotics
Content: participants received antipsychotic therapy such as chlorpromazine, clozapine, perphenazine, and risperidone, and also received MECT. The ECT device was Thymatron.
Frequency: 3 times a week for MECT; not stated for antipsychotics
Course of treatment (MECT): 12 sessions
Treatment duration: 28 days
Control group (n = 37): Antipsychotics alone
Content: participants received antipsychotic therapy such as chlorpromazine, clozapine, perphenazine, and risperidone.
Frequency: not stated
Treatment duration: 28 days
Outcomes Mental state: assessed by SAPS, SANS
Unable to use:
Response to treatment (data not reported)
Notes Contact information: Shaoyang Psychiatric Hospital, Shaoyang, Hunan, China
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "...were divided randomly into two groups..." (p.29)
Comments: The author described a random component in the sequence generation process, but no details were provided on randomisation method.
Allocation concealment (selection bias) Unclear risk Comments: The author did not describe the allocation concealment. Insufficient information to permit judgement of 'low risk' or 'high risk'.
Blinding of participants and personnel (performance bias) 
 All outcomes High risk Comments: The participants and personnel could not be blinded as 1 group did not use ECT, and no sham‐ECT was used.
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Comments: The author did not describe the blinding of outcome assessment. Insufficient information to permit judgement of 'low risk' or 'high risk'.
Incomplete outcome data (attrition bias) 
 All outcomes Low risk Comments: No missing outcome data.
Selective reporting (reporting bias) High risk Comments: The protocol is not available; all outcomes stated in methods other than overall efficiency rate reported in results.
Other bias Low risk None obvious.