Box-and-whisker plots of imaging modality–defined tumor-volume change over time in patients with imaging abnormalities noted at both time points. Significant volume reductions were observed after RT for T2FLAIR MRI–defined tumor and for 11C-methionine PET–defined tumor. Included are medians (connecting horizontal lines), means (diamonds), interquartile ranges (boxes), minimum and maximum values (whiskers), and outliers, that is, values beyond 1.5 interquartile ranges (circles).