Fig 5. Phosphatidylserine activates the BDNF-mediated signaling pathway.

(A-H) FD cells were treated with 50 μg/ml PS or a vehicle only control, and RNA was extracted 5 days after the treatment. qPCR was used to quantify (A) WT IKBKAP, (B) CDKN1A, (C) HOMER1, (D) RASSF8, (E) EGR1, (F) SRXN1, (G) RGS17, and (H) BAIAP2 mRNA transcripts. All values were normalized to LZIC, which did not change as a result of PS treatment. Asterisks denote statistically significant differences (*P ≤ 0.05 and **P ≤ 0.01) relative to control (vehicle only); Student’s t-test.