. 2019 Mar 7;17(3):e3000157. doi: 10.1371/journal.pbio.3000157

Table 1. AlloP and the photolabeling analogues modulate and activate α₁β₃-GABA_A receptor currents in X. laevis oocytes, tested by two-electrode voltage clamp.

Neurosteroids	Potentiation 1 μM NS	Potentiation 10 μM NS	Direct activation 10 μM NS
KK123	4.2 ± 3.3 (5)	8.2 ± 6.7 (7)	6.3 ± 3.8 (5)
KK200	1.6 ± 0.2 (5)	4.9 ± 2.7 (5)	0.14 ± 0.08 (5)
KK202	1.4 ± 0.2 (6)	3.9 ± 2.1 (9)	8.97 ± 8.9 (6)
	Potentiation 0.1 μM AlloP	Potentiation 1 μM AlloP	Direct activation 10 μM AlloP
AlloP	4.9 ± 1.3 (7)	9.7 ± 4.7 (7)	3.4 ± 1.2 (5)

Potentiation is expressed as potentiation response ratio, calculated as the ratio of the peak response in the presence of GABA and neurosteroids to the peak response in the presence of GABA alone. Direct activation is expressed as percentage of the response to saturating GABA. Data are shown as mean ± SD (number of cells).

Abbreviation: AlloP, allopregnanolone; GABA_A, gamma amino-butyric acid Type A; NS, neurosteroid.

Table 1. AlloP and the photolabeling analogues modulate and activate α1β3-GABAA receptor currents in X. laevis oocytes, tested by two-electrode voltage clamp.

Table 1. AlloP and the photolabeling analogues modulate and activate α₁β₃-GABA_A receptor currents in X. laevis oocytes, tested by two-electrode voltage clamp.