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. 2019 Mar;60(4):965–977. doi: 10.1167/iovs.18-26216

Figure 9.

Figure 9

HSF1 overexpression decreases leukostasis in the retina after IR injury. Representative images of leukostasis in the peripheral retinas. WT and HSF1-Tg mice were subjected to IR and leukostasis assay was performed at 24 hours after IR. Green: Con A-labeled retinal vasculature and adherent leukocytes. Red: CD45 immunostaining for leukocytes. Rectangle in the left rows of images are zoomed in and arrows indicate stationary leukocytes adherent to the vascular endothelium. Bar graphs represents the number of leukocytes adherent to the retinal vasculature (Con A+, CD45+) per retina and infiltrated leukocytes (Con A− , CD45+) per field. N = 4 mice; *P < 0.05 versus relevant control, #P < 0.05 HSF1-Tg IR versus WT IR.