REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
CD11c	Biolegend	117304 N418
CD3e	Biolegend	100304 145–2C11
NK1.1	Biolegend	108704 PK136
IL-7Ra	Biolegend	135006 A7R34
Ter-119	Biolegend	116204 TER-119
CD11b	Biolegend	101204 M1/70
CD8a	Biolegend	100704 53–6.7
CD4	eBioscience	13–0041-82 gk1.5
B220	Biolegend	103204 RA3–6B2
CD19	Biolegend	115504 6D5
GR-1	Biolegend	108403 RB6–8C5
CD45.1 PE	Biolegend	110708 a20
CD45.2 eflour 450	eBioscience	48–0454-82 104
GR1 APC	Biolegend	108412 RB6–8C5
CD3E FITC	Biolegend	100306 145–2C11
CD11B PE/CY5	Biolegend	101209 M1/70
CD45.2 PE/CY5	Biolegend	25–0454-80 104
CD3E PE/CY5	eBioscience	100310 145–2C11
IL-7Ra PE/CY5	Biolegend	135016 A7R34
NK1.1 PE/CY5	Biolegend	108716 PK136
GR1 PE/CY5	Biolegend	108410 RB6–8C5
cd11B PE/CY5	Biolegend	101209 M1/70
CD19 PE/CY5	Biolegend	115510 6D5
CD4 PE/CY5	BIolegend	15–0041–82 GK1.5
TER-119 PE/CY5	EBioscience	116209 TER-119
FC BLOCK	Biolegend	101302 93
CD150 PE/CY7	Biolegend	115914 TC15–12F12.2
CD45.2 APC/CY7	Biolegend	109824 104
CD34 EFLOUR450	Biolegend	48–0341–80 RAM34
CD34 PE	EBioscience	128610 HM34
IL-7Ra PE	Biolegend	135009 A7R34
CD48 PACBLUE	Biolegend	103418 HM48–1
CD61 PE	Biolegend	12–0611–82 2C9.G3
CD38 APC/CY7	EBioscience	102728 90
CD34 APC/CY7	BIolegend	128614 HM34
CD16/32 EFLOUR450	Biolegend	48–0161–82 93
CD16/32 VIOLET 420	EBioscience	101331 93
CD16/32 PE/CY7	Biolegend	25–0161–81 93
SCA1 APC	EBioscience	108112 D7
SCA1 PACBLUE	Biolegend	108120 D7
CKIT APC	Biolegend	105812 2B8
CKIT PE	Biolegend	1335106 ACK2
CKIT FITC	Biolegend	105806 2B8
CD135 APC	Biolegend	135310 A2F10
CD41 PE	Biolegend	133906 B203323
CD51 PE	Biolegend	104106 B240646
CD61 APC	Biolegend	104316 B219725
Bacterial and Virus Strains
PCL-ecotropic pseudotyped gamma-retrovirus	O'Connell et al. J Exp Med. 2008 Mar 17. 205(3):585–94.	Adgene: #26528
Chemicals, Peptides, and Recombinant Proteins
LPS	SIGMA	L2880–100MG
Pam3CSK4	Invivogen	41–11–60–10
Dulbecco's Modification of Eagle's Medium	Corning	10–013-CV
Fetal Bovine Serum	Corning	35–015-CV
Penicillin Streptomycin Solution (100x)	Corning	30–002-Cl
0.25% Trypsin	Corning	25–053-Cl
TRIzol Reagent	Invitrogen	15596026
Protoscript II	New England Biolabs	M0368L
Antarctic phosphatase	New England Biolabs	M0289S
Puromycin	InvivoGen	Cat#ant-pr-1
Murine SCF	PeproTech	250–03
Murine IL-6	PeproTech	216–16
Murine IL-3	PeproTech	213–13
Critical Commercial Assays
BioT	Bioland	B01–01
Nextera XT DNA Library Preparation Kit	illumina	FC-131–1096
qScript cDNA SuperMix	Quanta	95048–100
KAPA HiFi HotStart ReadyMix	KAPA biosystems	KM2602
Deposited Data
RNA-Seq Gene Expression and IR Data	This Paper	GEO: GSE100428
Experimental Models: Cell Lines
HEK293T	ATCC	CRL-3216
Experimental Models: Organisms/Strains
Mouse: C57BL/6J	Jackson Laboratory	000664
Mouse: C57BL/6J	Charles Rivers Laboratories	C57BL/6NCrl
Oligonucleotides - source
Primers used	Table S5	This paper
shRNA sequences	Table S5	This paper
cDNA sequences for transcription factors over expression	Table S5	This paper