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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Prostate. 2018 Jul 15;78(15):1140–1156. doi: 10.1002/pros.23689

Figure 7. Ad-E1A12 in combination with pharmacological mTOR inhibition effectively kills PCa cells with AR expression.

Figure 7.

PCa cell lines LNCaP (A), PC-3 (B) and R1-AD1 and its derivatives (C, D and E) were infected with Ad-eGFP or Ad-E1A12 at the indicated MOIs. These cell lines were also treated with DMSO (control), an indicated mTOR inhibitor at 0.1 μM alone, or together with the viruses at various MOIs as indicated. Cell viability assays were conducted at 96 h post infection with CellTiter-Glo assay kit. Shown are average values along with SEM of three experiments. Tem: temsirolimus. The P values were calculated using Student’s t test.