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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Neurobiol Dis. 2018 Sep 10;121:65–75. doi: 10.1016/j.nbd.2018.09.002

Figure 2. Tadalafil does not affect IOP measurements in either POAG or PACG murine models of glaucoma.

Figure 2.

IOP was measured over time in WT or GC-1−/− mice in the POAG model of glaucoma, and in WT mice with and without microbead injection in the PACG model. A) IOP in WT mice does not change with tadalafil treatment, B) IOP in GC-1−/− mice does not change with tadalafil treatment and C) tadalafil treatment does not alter IOP in the PACG murine model of glaucoma in WT mice. Data expressed as mean ± S.D. Statistical significances between saline and MOM (microbead occlusion model) groups are p<0.0002 for all comparisons.