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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Neurobiol Dis. 2018 Sep 10;121:65–75. doi: 10.1016/j.nbd.2018.09.002

Figure 5. Tadalafil prevents RGC loss in the murine PACG model of glaucoma.

Figure 5.

Retina were flatmounted and stained for βIII tubulin. A) Representative βIII tubulin-stained RGC micrographs in WT mice maintained on control or tadalafil chow for 1 month after saline or microbead injection are shown, scale bar = 50μM. B) Quantitative analysis of the mean density of βIII tubulin-positive RGCs (y-axis; mean RGCs/mm2 ± S.D) in retina reveals decreased RGC density in mice injected with microbeads that is reversed by tadalafil treatment. *** p<0.0001. MOM = microbead occlusion model.