Skip to main content
. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Neurobiol Dis. 2018 Sep 10;121:65–75. doi: 10.1016/j.nbd.2018.09.002

Figure 6. Tadalafil prevents ON axon depletion in the murine PACG model of glaucoma.

Figure 6.

A) Representative PPD-stained ON axon micrographs in WT mice on control or tadalafil chow for 1 month after saline or microbead injection, scale bar = 10μM. B) Quantitative analysis of the mean density of RGC axons (y-axis; mean axons/mm2 ± S.D) in optic nerve reveals decreased RGC axon density in microbead-injected mice that is reversed by tadalafil treatment. Data expressed as mean ± S.D. **** p<0.0001. MOM = microbead occlusion model.