Table 2:
Association between cord plasma adiponectin levels and ASD risk in children in the Boston Birth Cohorta
| Unadjusted | Model 1 | Model 2 | Model 3 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total n | ASD n | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |
| Continuous | 674 | 40 | 0.51 (0.35, 0.75) | 0.001 | 0.50 (0.33, 0.77) | 0.002 | 0.47 (0.30, 0.74) | 0.001 | 0.36 (0.21, 0.62) | <0.001 |
| Quartile | ||||||||||
| Q1 | 167 | 20 | Ref | Ref | Ref | Ref | ||||
| Q2 | 170 | 8 | 0.36 (0.16, 0.85) | 0.02 | 0.39 (0.15, 1.01) | 0.05 | 0.38 (0.14, 1.03) | 0.06 | 0.32 (0.11, 0.91) | 0.03 |
| Q3 | 169 | 7 | 0.32 (0.13, 0.77) | 0.01 | 0.40 (0.15, 1.10) | 0.08 | 0.38 (0.13, 1.12) | 0.08 | 0.23 (0.07, 0.77) | 0.02 |
| Q4 | 168 | 5 | 0.23 (0.08, 0.62) | 0.004 | 0.14 (0.04, 0.46) | 0.001 | 0.13 (0.04, 0.45) | 0.001 | 0.08 (0.02, 0.34) | 0.001 |
a
Adiponectin was entered as a continuous variable in one model and categorical variable in another model
Model 1: Adjusted for child’s sex, race, maternal education, maternal age, parity, smoking status, pre-pregnancy BMI, diabetes status, follow-up time
Model 2: Model 1 + gestational age
Model 3: Model 1 + early childhood adiponectin