Table 3:
Association between early childhood plasma adiponectin levels and ASD risk in children in the Boston Birth Cohorta
| Unadjusted | Model 1 | Model 2 | Model 3 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Total n | ASD n | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | OR (95% CI) | p value | |
| Continuous | 638 | 36 | 0.71 (0.45, 1.13) | 0.15 | 0.54 (0.33, 0.90) | 0.02 | 0.59 (0.35, 0.99) | 0.05 | 0.67 (0.34, 1.33) | 0.25 |
| Quartile | ||||||||||
| Q1 | 160 | 11 | Ref | Ref | Ref | Ref | ||||
| Q2 | 159 | 8 | 0.72 (0.28, 1.83) | 0.49 | 0.68 (0.25, 1.85) | 0.45 | 0.74 (0.26, 2.05) | 0.56 | 0.77 (0.19, 3.14) | 0.71 |
| Q3 | 160 | 10 | 0.90 (0.38, 2.19) | 0.82 | 0.71 (0.27, 1.90) | 0.50 | 0.84 (0.31, 2.29) | 0.73 | 0.85 (0.23, 3.11) | 0.80 |
| Q4 | 159 | 7 | 0.62 (0.24, 1.65) | 0.34 | 0.30 (0.09, 0.98) | 0.05 | 0.32 (0.10, 1.08) | 0.07 | 0.68 (0.15, 3.10) | 0.61 |
a
Adiponectin was entered as a continuous variable in one model and categorical variable in another model
Model 1: Adjusted for maternal age, diabetes status, maternal BMI, sex, race, age of measurement, follow-up time and breastfeeding status
Model 2: Model 1 + gestational age at birth
Model 3: Model 1 + cord adiponectin