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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Immunol. 2019 Feb 11;202(7):2017–2026. doi: 10.4049/jimmunol.1801436

Figure 4. Anti-IL-17A and anti-TNFα combination therapy causes minimal susceptibility to tuberculosis.

Figure 4.

(A) Left: Study design. Right: Survival rate after infection over 49 days. N=8 mice per group. Differences were determined using Log-Rank Test compared to isotype control group. (B) Bacterial loads were measured in the homogenates from the indicated organs on day 49 p.i. using agar plates. (C) Concentrations of indicated cytokines in lung homogenates at day 49 measured by Luminex. N=8 mice/group. Bacterial load or cytokine concentrations ere analyzed by one-way ANOVA with Dunnett’s post-testing using the isotype group as control. *P < 0.05, ** < 0.01 and *** < 0.001.