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editorial
. 2019 Mar;11(Suppl 3):S296–S299. doi: 10.21037/jtd.2019.01.23

Table 2. Estimated size effect of treatment with Simvastatin and required sample size.

Study population Mortality rate placebo group (%) Absolute effect size (%) NNT Required sample size
HARP-2 25 4.5 22 2,722
Enrichment hyper-inflammatory phenotype 45 13 8 438

NNT, number needed to treat.