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. Author manuscript; available in PMC: 2019 Mar 20.
Published in final edited form as: Methods Mol Biol. 2018;1757:399–470. doi: 10.1007/978-1-4939-7737-6_14

Table 4.

Major GO annotation pipelines at WormBase1

Annotation
Pipeline		 Associated Evidence
Codes		 Sample gcy-8
Annotation
Manual, literature-based IMP, IGI, IDA, IPI, ISS, IEP, IC, ISM, ND, TAS, NAS thermotaxis
Phylogenetic based on PANTHER families2 IBA, IKR signal transduction
UniProt Keyword (KW) Mappings3 IEA cGMP biosynthetic process
InterPro2GO Mappings3,4 IEA cyclic nucleotide biosynthetic process
Enzyme Commission (EC) Mappings3 IEA guanylate cyclase activity
UniProt Subcellular Localization (SL)3 IEA plasma membrane
1

Other annotation pipelines include UniPathway and UniRule (Huntley et al., 2015, PMID:25378336 [23]).

2

Gaudet et al., 2011, PMID:21873635 [22]

3

Huntley et al., 2015, PMID:25378336 [23]

4

Mitchell et al., 2015, PMID:25428371 [11]