Table 2. Correlation between CT Parameters and Pulmonary Function Indices According to GOLD Criteria.
| CT/Clinical Parameters | FEV1/FVC | FEV1 | DLCO |
|---|---|---|---|
| GOLD I | |||
| CT ATI | -0.36 (< 0.001) | -0.05 (0.60) | 0.11 (0.24) |
| Inspiratory MLD | 0.45 (< 0.001) | 0.02 (0.82) | -0.17 (0.07) |
| EI | -0.46 (< 0.001) | -0.03 (0.72) | 0.08 (0.41) |
| Wall thickness | -0.02 (0.87) | 0.03 (0.79) | 0.14 (0.13) |
| WA% | -0.01 (0.89) | 0.05 (0.61) | 0.12 (0.21) |
| Pi10 | -0.02 (0.86) | 0.02 (0.84) | 0.13 (0.17) |
| BMI | 0.26 (0.004) | 0.13 (0.15) | -0.01 (0.91) |
| 6-min walk test, m | 0.09 (0.33) | 0.09 (0.34) | 0.10 (0.29) |
| Initial SpO2 | 0.11 (0.25) | 0.07 (0.50) | 0.23 (0.02) |
| Post SpO2 after 6-min walk test | 0.20 (0.04) | 0.12 (0.21) | -0.03 (0.78) |
| GOLD II | |||
| CT ATI | -0.07 (0.39) | -0.10 (0.24) | -0.05 (0.58) |
| Inspiratory MLD | 0.38 (< 0.001) | 0.11 (0.18) | 0.16 (0.06) |
| EI | -0.37 (< 0.001) | -0.17 (0.05) | -0.20 (0.02) |
| Wall thickness | 0.17 (0.05) | 0.70 (0.42) | 0.25 (0.003) |
| WA% | 0.15 (0.08) | 0.05 (0.56) | 0.20 (0.02) |
| Pi10 | 0.16 (0.06) | 0.06 (0.52) | 0.22 (0.01) |
| BMI | 0.13 (0.12) | 0.09 (0.31) | 0.04 (0.67) |
| 6-min walk test, m | 0.12 (0.17) | -0.10 (0.25) | -0.10 (0.24) |
| Initial SpO2 | 0.02 (0.86) | 0.02 (0.81) | 0.09 (0.29) |
| Post SpO2 after 6-min walk test | 0.002 (0.98) | 0.06 (0.50) | -0.03 (0.71) |
| GOLD III | |||
| CT ATI | -0.32 (0.001) | -0.30 (0.003) | -0.23 (0.03) |
| Inspiratory MLD | 0.59 (< 0.001) | 0.30 (0.003) | 0.24 (0.02) |
| EI | -0.55 (< 0.001) | -0.35 (< 0.001) | -0.25 (0.01) |
| Wall thickness | 0.15 (0.13) | -0.10 (0.34) | 0.14 (0.16) |
| WA% | 0.23 (0.02) | 0.03 (0.76) | 0.10 (0.34) |
| Pi10 | 0.21 (0.04) | -0.003 (0.98) | 0.13 (0.20) |
| BMI | 0.19 (0.06) | 0.06 (0.56) | 0.04 (0.67) |
| 6-min walk test, m | 0.18 (0.08) | 0.23 (0.02) | 0.16 (0.13) |
| Initial SpO2 | 0.05 (0.65) | -0.02 (0.84) | 0.29 (0.005) |
| Post SpO2 after 6-min walk test | 0.16 (0.13) | 0.18 (0.08) | 0.08 (0.42) |
| GOLD IV | |||
| CT ATI | -0.42 (0.11) | -0.14 (0.61) | 0.35 (0.18) |
| Inspiratory MLD | 0.29 (0.28) | -0.05 (0.85) | -0.05 (0.85) |
| EI | -0.36 (0.18) | 0.15 (0.58) | 0.13 (0.64) |
| Wall thickness | 0.21 (0.43) | -0.11 (0.68) | 0.06 (0.83) |
| WA% | 0.21 (0.43) | -0.10 (0.70) | -0.01 (0.97) |
| Pi10 | 0.16 (0.56) | -0.20 (0.45) | 0.08 (0.77) |
| BMI | -0.18 (0.51) | 0.11 (0.70) | -0.50 (0.05) |
| 6-min walk test, m | -0.21 (0.43) | -0.38 (0.15) | -0.35 (0.19) |
| Initial SpO2 | 0.24 (0.36) | -0.32 (0.23) | 0.07 (0.79) |
| Post SpO2 after 6-min walk test | 0.49 (0.05) | -0.27 (0.32) | -0.17 (0.53) |
Data are Pearson r correlation values. Numbers in parentheses are p values.