Table 1. Predictors of Treatment Response to Chemotherapy.
| Parameters | Responders (n = 6) | Non-Responders (n = 15) | P* |
|---|---|---|---|
| PCT | |||
| BF (mL/100 g/min) | 46.5 ± 14.7 | 51.4 ± 17.6 | 0.569 |
| BV (mL/100 g) | 11.2 ± 3.8 | 11.0 ± 3.7 | 0.970 |
| TTP (seconds) | 16.0 ± 1.7 | 15.0 ± 1.5 | 0.267 |
| MTT (seconds) | 13.3 ± 3.8 | 10.3 ± 3.5 | 0.095 |
| PS (mL/100 g/min) | 51.0 ± 29.5 | 23.4 ± 8.4 | 0.002 |
| Age (years) | 59.7 ± 5.5 | 51.3 ± 16.2 | 0.080 |
| Sex (male:female) | 5:1 | 8:7 | 0.201 |
| Histologic subtype (PCC:non-PCC) | 1:5 | 5:10 | 0.623 |
| Differentiation (M/D:P/D) | 1:5 | 4:11 | 1.000 |
Data are means ± standard deviation. *p values were determined by Fisher's exact test for categorical variables and Mann-Whitney U test for continuous variables. BF = blood flow, BV = blood volume, M/D = moderately-differentiated, MTT = mean transit time, PCC = poorly cohesive carcinoma, PCT = perfusion CT, P/D = poorly-differentiated, PS = permeability surface, TTP = time to peak