Fig. 2. Three cervical screening strategies to detect CIN2+/CIN3+. Effectiveness analysis of cervical screening strategies: primary screening algorithms. (A) Strategy I was co-testing, cytology combined with HPV using as the primary detection. (B) Strategy II was primary cytological detection with triaged by HPV testing. (C) Strategy III was primary HR-HPV testing with HPV-16/-18 genotype. In different strategies, the cases with ≥CIN2+ detected in the baseline screening, first year recall and the subsequent follow-up were listed in Fig. 2.

ASC-US, atypical squamous cells of undetermined significance; CIN, cervical intraepithelial neoplasia; HPV, human papillomavirus; HR-HPV, high-risk human papillomavirus; NILM, negative for intraepithelial lesion or malignancy.