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. 2019 Mar 19;7(6):e14036. doi: 10.14814/phy2.14036

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© 2019 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Histology of mouse hearts stained with picrosirius red. Panel B compared to A shows minimal fibrosis in Meth‐treated female mouse heart, whereas the single male mouse that survived 5 months of treatment (panel D) had substantial fibrosis.