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. 2019 Mar 13;10:416. doi: 10.3389/fimmu.2019.00416

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Copyright © 2019 Xu, Negandhi, Min, Tsui, Post, Harrison and Grunebaum.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Thymus analysis of 17 days pp ADA+/– mice, ADA–/– mice, and ADA–/– mice following ERT. Thymus weight (A), thymocytes numbers (B), and percentages of CD4+CD8+ thymocytes (C) of 17 days postpartum (pp) ADA+/– healthy littermate control mice (filled squares), ADA–/– mice (open squares), and ADA–/– mice that received ERT initiated at 7 days pp (stripe pattern). Results are the mean and standard deviation of 3 independent experiments of 4–6 mice in each group.