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. 2019 Mar 13;13:92. doi: 10.3389/fncel.2019.00092

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Copyright © 2019 Sapir, Segal, Grigoryan, Hansson, James, Segal and Reiner.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Summary of recordings from wild-type controls and Ppt1 KO cells. (A) Illustration of spontaneous miniature EPSCs recorded from a cultured neuron voltage clamped at −60 mV. Left, a continuous record at low speed, right a zoomed trace taken from the left record. Scale 20 pA for both, 10 s and 5 ms for the left and right traces, respectively. (B) Means of discharge rates of 16 controls and 18 Ppt1−/− cells. (A) Significant reduction in discharge rate is seen (t-test, *p < 0.02). (C,D) No difference in amplitudes (C) or rise time (D) between the same two groups is detected.