Table 2.
Parameters | NonCI-patients | CI-patients | P-value |
---|---|---|---|
n = 33 | n = 10 | ||
EPIDEMIOLOGICAL DATA | |||
Age; years | 37.4 ± 13.5 | 34.0 ± 11.3 | 0.542 |
Gender: male/female | 22/11 | 9/1 | 0.150 |
Body mass; kg | 87.2 ± 15.4 | 101 ± 27 | 0.204 |
BMI; kg/m2 | 27.6 ± 4.1 | 31.3 ± 6.2 | 0.033 |
DISEASE SPECIFIC DATA | |||
Duration of disease (years) | 10.7 ± 9.8 | 11.6 ± 8.0 | 0.702 |
PANSS | 70.0 ± 6.6 | 67.1 ± 5.5 | 0.724 |
MEDICATION | |||
Chlorpromazine equivalents, CPE (mg/d) | 624 ± 632 | 767 ± 822 | 0.687 |
Clozapin (yes/no) | 2/31 | 3/7 | 0.039 |
PARAMETERS OF AEROBIC FITNESS | |||
Peak oxygen uptake; ml/kg/min | 30.9 ± 8.6 | 25.2 ± 7.5 | 0.067 |
Peak oxygen uptake; % pred | 98 ± 21 | 74 ± 19 | 0.003 |
Peak power output; W/kg | 1.97 ± 0.52 | 1.54 ± 0.49 | 0.027 |
Power output at Lactate Threshold; W/kg | 1.06 ± 0.33 | 0.83 ± 0.21 | 0.017 |
PWC 130; W/kg (CI: n = 9; nonCI: n = 31) | 1.08 ± 0.33 | 1.14 ± 0.29 | 0.601 |
PWC 150; W/kg (CI: n = 9) | 1.39 ± 0.45 | 1.61 ± 0.34 | 0.188 |
OBJECTIVE EFFORT | |||
Peak blood lactate, mmol/l | 7.9 ± 2.6 | 6.4 ± 2.3 | 0.089 |
HEART RATE DATA AND CHRONOTROPIC RESPONSE | |||
Baseline heart rate; 1/min | 88 ± 15 | 92 ± 7 | 0.629 |
Peak heart rate; 1/min | 177 ± 14 | 154 ± 17 | <0.001 |
% pred. heart rate reserve | 95 ± 13 | 64 ± 13 | <0.001 |
Slope metabolic-chronotropic relationship | 0.98 ± 0.14 | 0.65 ± 0.15 | <0.001 |
Data shown as mean ± standard deviation or absolute numbers.
n, number of participants if not all are include in calculation because of excluded or missing data (e.g., failure to reach a given heart rate).
Bold values indicate significant differences between groups.