Figure 1.

(A) Schematic diagram of the differentiation and development of DC subsets and the metabolic regulation factors that modulate these processes. (B) Different in vitro culture system for the generation of DCs from mouse bone marrow progenitors, or human peripheral blood mononuclear cells, CD14+ monocytes, or CD34+ Hemopoietic progenitor cells. The metabolic regulation factors were also listed. Positive regulators were in the red color, negative regulators were in the green color, regulators that affected the homeostasis of DC subsets were in the black color, regulator that is controversial for its role were in the orange color.