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Effect of acute water load on plasma copeptin. Plasma copeptin concentration [expressed as mean (95 CI)] measured minutes after 1 L water intake (n = 39). At 0 min, median (IQ) copeptin value is 5.05 (3.53–6.44) pmol/L, whereas it decreases to 2.77 (2.28–3.57) pmol/L at 90 min. *p < 0.001
