Fig. 2.

MiRNAs in adipogenesis. MiRNAs influence adipogenesis during determination phase, which is the conversion of mesenchymal stem cell to preadipocytes, clonal expansion, and terminal differentiation of preadipocyte to mature adipocyte. MAPK mitogen-activated protein kinase, ERK extracellular signal-regulated kinase, MSC mesenchymal stem cell, cAMP cyclic adenosine monophosphate, CREB cAMP response element-binding, WNT wingless and INT-1, TCF T-cell-specific transcription factor, PPAR peroxisome proliferator-activated receptor, C/EBP CCAAT/enhancer-binding protein, KLF Kruppel-like factor, IRS insulin receptor substrate, PKB protein kinase B, GSK glycogen synthase kinase 3