Table 1.
The degree of the changes in different rat organs after been treated with toxic and non-toxic doses of GNPs in the three tested rat groups
| Organs and parameters | Groups | ||
|---|---|---|---|
| Control | The group which received non toxic dose of GNPs | The group which received toxic dose of GNPs | |
| Kidney | |||
| Changes in the glomeruli | 0 | 1 | 1 |
| Changes in the Bowman’s capsules | 0 | 0 | 0 |
| Changes in the proximal and distal tubules | 0 | 0 | 0 |
| Present of the hyperemia and inflammation | 0 | 0 | 1 |
| Liver | |||
| Changes in the hepatocytes structure | 0 | 1 | 1 |
| Changes in the lobular central vein | 0 | 1 | 0 |
| Changes in the portal tract | 0 | 0 | 0 |
| Changes in the sinusoidal space | 0 | 0 | 1 |
| Testis | |||
| Changes in the seminiferous tubules | 0 | 0 | 1 |
| Changes in the spermatogenic cells | 0 | 0 | 0 |
| Changes in the sertoli cells | 0 | 0 | 0 |
| Changes in the interstitial tissue and leydig cells | 0 | 0 | 1 |
In the table, 0 represented no changes, 1 represented mild changes, 2 represented the middle and 3 represented the maximum changes