Table 1.
Effect of various treatments on wound healing parameters in the excision and incision wound models at an optimized dose
| Groups optimized dose (70 mg/g ointment) except for control | Wound area (mm2) excision model | Epithelization period (days) | Breaking strength (g) incision model | Hydroxyproline (mg/g) |
|---|---|---|---|---|
| 12th day | – | 10th day | 15th day | |
| 1.Control | 66.34 ± 1.70 | 33.00 ± 1.26 | 272.96 ± 1.30 | 30.21 ± 1.18 |
| 2. Placentrex | 15.97*** ± 1.39 | 15.16*** ± 1.16 | 653.44*** ±1.05 | 80.23*** ± 1.44 |
| 3. Seed extract | 50.63 ** ± 1.02 | 27.00*** ± 1.67 | 312.21 ** * ± 1.06 | 40.22*** ± 0.75 |
| 4. Flavonoid fraction | 40.06*** ± 1.06 | 24.50*** ± 1.51 | 467.43*** ± 1.26 | 62.45*** ± 1.92 |
| 5.Mlf@AuNps | 35.62*** ± 1.65 | 21.33*** ±1.50 | 612.85*** ±1.80 | 68.11*** ± 0.77 |
| 6.Mlf@AgNps | 19.67*** ± 1.08 | 18.00*** ± 1.41 | 624.23*** ± 1.30 | 76.23***± 1.38 |
| 7. Mlf@Au–AgNps | 34.02***±1.62 | 21.00*** ±1.50 | 616.01*** ± 1.55 | 70.03*** ± 1.42 |
Each value is the mean ± SD of six mice (n = 6) at ***p < 0.001