Figure 5.

Effects of As₂O₃, GSPE, and BAY 11–7082 on the mRNA expression of IκB-α, IKKα, IKKβ, NF-κBp65, and NF-κBp50 in BEAS-2B cells. The BEAS-2B cells were treated with 5 μmol/L As₂O₃ (n = 10) and GSPE (50 mg/L) and BAY 11–7082 (50 mg/L) were used to antagonize the effects of arsenic. The relative mRNA levels were determined by RT-PCR using gene-specific primers. Values are expressed as means ± SD. ^aP < 0.05, compared with the blank control group; ^bP < 0.05, compared with the arsenic group. (A color version of this figure is available in the online journal.)

GSPE: grape seed proanthocyanidin extract.